Philadelphia Eagles vs. San Francisco 49ers Betting Odds Analysis and Prediction

The Philadelphia Eagles are one of just three undefeated teams left in the NFL after the first three weeks, but they will face their toughest test of the young season when they visit the San Francisco 49ers Sunday.

Fortunately for the Eagles, they have enjoyed a lot of past success against San Francisco, winning five of the last six meetings both straight up and against the spread.

Point spread: The 49ers opened as 4.5-point favorites, but the number was climbing. Meanwhile, the total was hovering around 50.5 (line updates and matchup report).
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