San Francisco 49ers vs. Arizona Cardinals: Spread Info, Line and Predictions

The San Francisco 49ers have already clinched the NFC West, but the dejected Arizona Cardinals proved last week with their win over the Cowboys that they haven't lost the motivation to play.

The Cardinals got spanked 23-7 the last time they saw the Niners, but will Patrick Willis' hamstring injury, the recent success the Cardinals have seen and home-field advantage be enough to power the Cardinals past the 49ers?

Let's take a closer look at how these two teams match up.

Where: University of Phoeni...

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